Residence Inn by Marriott is a brand of extended stay hotels. As of June 1, 2021, there were 874 Residence Inn hotels in the United States, Canada and Mexico with 107,680 rooms, plus an additional 243 hotels with 30,417 rooms in the development pipeline.

The chain traces its roots back to in 1975, when Wichita, Kansas developer Jack DeBoer found himself with apartment properties that were facing unusually high vacancy rates. He repurposed one of the apartment buildings, converting the residential units to monthly rentals, and named it The Residence.